Zonci XL120 Semi-Automated Coagulation Analyzer
The Zonci XL120 is a benchtop semi-automated coagulation analyzer with 2 independent testing channels for up to 120 PT tests/hour using optical detection. Suited for small labs and clinics, it measures PT, APTT, TT, FIB, and more via turbidity-based clotting, features manual pipetting, reagent pre-heating, LCD display, built-in printer, and data export for affordable, reliable clotting time analysis in plasma samples.
Description
Coagulation Parameters: Essential Hemostasis Screening The Zonci XL120 focuses on fundamental clotting assessments, including prothrombin time (PT) for extrinsic pathway, activated partial thromboplastin time (APTT) for intrinsic, thrombin time (TT) for fibrinogen conversion, and fibrinogen (FIB) quantification, with support for extended tests like D-Dimer (D-D) and factor assays. This streamlined panel aids in detecting coagulation deficiencies, monitoring oral anticoagulants, or evaluating bleeding risks, providing essential data for primary care, surgical pre-ops, or small hospital settings with straightforward, cost-effective results.
Parameters Measured: Evaluates up to 10 parameters with solid linearity (e.g., PT 9.9–99.9 s, APTT 32–120 s, TT 10–99 s, FIB 0.3–6.5 g/L), employing optical turbidity detection for endpoint determination insensitive to sample turbidity or mild hemolysis. Displays reaction curves and computes times via threshold algorithms, with QC flags and alarms for out-of-range values to maintain <4% CV, ensuring compliance with CLSI guidelines for basic hemostasis in resource-limited environments.
Sample Requirements: Requires 50–100 µL of citrated plasma via manual pipetting into disposable cuvettes, accommodating venous draws from standard tubes. Supports single or batch testing without dilution for routine ranges, with low sample volume ideal for pediatric or serial monitoring, minimizing waste and pre-analytical steps in manual workflows.
Throughput: Processes up to 120 PT tests per hour across 2 parallel channels, tailored for small clinics handling 100–300 tests daily. Manual loading with rapid 1–3 minute TAT per sample enables flexible, on-demand operation, suitable for STAT requests like pre-procedure PT checks without the overhead of full automation.
Technology: Utilizes optical detection based on light scatter changes during fibrin formation, with LED source (470 nm) and photodiode sensors for precise endpoint capture in 37°C incubated cuvettes. Includes magnetic stirring for uniform mixing and digital signal processing to filter noise; simple 2-point calibration and daily QC routines align with ISTH standards for dependable performance with minimal training.
User Interface and Storage: Features a clear LCD display for real-time test monitoring, results, and curves, with membrane keypad controls and multilingual support (up to 4 languages, including English and Chinese) for user-friendly handling. Stores up to 500 results with patient IDs and QC data; built-in thermal printer for immediate reports with basic templates, plus RS232 port for data transfer to PC/LIS and simple CSV exports for record-keeping.
Reagent System: Open system with 4 pre-heating positions (37°C) for liquid reagents, compatible with Zonci’s economical kits (e.g., PT/APTT thromboplastin). Low consumption (20–40 µL/test) and manual calibration extend usability to 24 hours, with visual indicators for low stock to support budget-conscious operations in decentralized labs.
Dimensions and Portability: Ultra-compact design measuring 220 × 250 × 100 mm (W × D × H) weighs just 3 kg, perfect for countertop or portable use in clinics or field settings. Low power (≤50 VA) and silent operation (<45 dB) suit 10–35°C ambient with 20–85% humidity, with battery option for brief offline testing.
- Throughput: Up to 120 PT tests/hour
- Detection Channel: 2 independent optical channels.
- Detection Principle: Optical turbidity with LED-photodiode for fibrin detection.
- Detection Items: PT, APTT, TT, FIB, D-Dimer, basic factor assays; alarms for abnormal times.
- Built-in thermal printer, supports external printers. Basic print templates available.
- 500 sample results, including parameters, reaction curves, and patient information.
- Sample modes: Citrated plasma; manual pipetting with cuvette-based testing.
