Maccura F810 5-Part Auto Hematology Analyzer
The Maccura F810 is an advanced 5-part hematology analyzer with CBC+DIFF+RET capabilities, offering 36 parameters + 4 histograms + scattergram at 100 tests/hour using 88 µL sample volume. Built for mid-to-large labs, it features fluorescence staining + flow cytometry for precise WBC/NRBC diff, laser scatter for RET, impedance for RBC/PLT, cyanide-free HGB, 10.4-inch touchscreen, 200,000-result storage, and built-in printer. Supports venous, capillary, pre-diluted, and body fluid modes with optional workstation connectivity for seamless, high-efficiency diagnostics.
Description
5-Part Differentiation: Advanced White Blood Cell Subpopulation Analysis The Maccura F810 leverages fluorescence nucleic acid staining and flow cytometry to deliver accurate 5-part WBC differentiation, quantifying neutrophils (NE# and NE%), eosinophils (EO# and EO%), basophils (BA# and BA%), monocytes (MO# and MO%), and lymphocytes (LY# and LY%). Enhanced by dedicated channels for basophils and nucleated red blood cells (NRBC), it sensitively detects immature leukocytes and naive cells, enabling reliable screening for peripheral blood abnormalities such as blasts in leukemias, eosinophilia in hypersensitivity reactions, or NRBC elevation in hemolytic anemias, with superior performance in complex samples from immunocompromised patients.
Parameters Measured: Quantifies 36 parameters (including 26+ reportable), spanning full CBC, DIFF, and RET profiles: WBC, NE#, EO#, BA#, MO#, LY#, NE%, EO%, BA%, MO%, LY%, NRBC#, NRBC%, RBC, HGB (via cyanide-free spectrophotometry for safer handling), HCT, MCV, MCH, MCHC, RDW-SD, RDW-CV, PLT, MPV, PDW, PCT, P-LCR, P-LCC, RET#, RET%, IRF (immature reticulocyte fraction), and reticulocyte maturity indices. Outputs four histograms (WBC, BASO, RBC, PLT) alongside a 2D scattergram and RET-specific plot for detailed visualization, with automated alarms for atypical lymphocytes, immature granulocytes, or reticulocyte shifts to expedite evaluation of erythropoiesis or thrombopoiesis disorders.
Sample Requirements: Employs a compact 88 µL sample volume to streamline testing in routine or low-volume scenarios like pediatrics or geriatrics. Versatilely handles venous whole blood for core lab efficiency, capillary blood for immediate POC results (e.g., fingerstick in emergencies), pre-diluted for broad linearity, and body fluid modes for ascitic or synovial analysis, maintaining precision across modalities with reduced hemolysis and artifact risks.
Throughput: Attains up to 100 samples per hour for CBC+DIFF (or combined RET modes), engineered for demanding labs processing 800–1,500 tests daily. The optional multi-instrument workstation configuration enables parallel operation with immunoassay or chemistry analyzers, incorporating auto-loading racks and intelligent reruns to optimize workflow, minimize hands-on time, and deliver first results in <45 seconds for critical STAT processing.
Technology: Combines fluorescence staining + hydrodynamic focusing flow cytometry + multi-angle laser scatter for WBC/DIFF/NRBC/RET detection, electrical impedance for RBC/PLT enumeration, and cyanide-free colorimetric method for HGB to foster eco-conscious labs. Independent channel isolation and specific DNA/RNA binding enhance resolution for low-abundance cells, achieving CVs <1.2% on key assays. Integrated AI algorithms for cell flagging and two-level QC align with CLSI/ICSH guidelines, while the system’s naive cell screening boosts early anomaly detection in oncology monitoring or infection surveillance.
User Interface and Storage: Integrates a 10.4-inch vibrant color touchscreen with dynamic 3D graphics, customizable dashboards, and multilingual capabilities (up to 12 languages, including English, Italian, Korean, and Chinese) for effortless, inclusive use. Manages 200,000+ results encompassing parameters, plots, demographics, and audit logs in a robust, query-optimized database. Onboard thermal printer supports diverse templates for compliant reporting, with USB/LAN/RS232/Ethernet connectivity for HL7-compliant LIS/HIS linkage, remote diagnostics, and secure exports in PDF/XML/CSV to meet ISO 15189 and CAP accreditation needs.
Reagent System: Closed architecture tailored to Maccura’s stable, low-waste reagents (e.g., MAK-Fluoro for nucleic acid staining, MAK-Cleaner for maintenance), with automated on-board tracking for up to 6 reagent slots including dye and waste management. Efficient dispensing cuts usage by 50%, with extended stability (up to 4 months) and real-time alerts for inventory, while dynamic linearity (WBC to 450 x 10^9/L) and auto-calibration routines reduce operational overhead in integrated workstation setups.
Dimensions and Portability: Streamlined benchtop form factor at 650 × 850 × 750 mm (W × D × H) weighs 55 kg, with modular expansion bays for workstation integration. Functions at <62 dB on AC 100–240V with ≤350 VA consumption, thriving in 10–35°C ambient and 20–85% humidity for flexible placement in centralized labs or automated lines.
- Throughput: Up to 100 samples/hour (CBC+DIFF+RET); expandable via workstation.
- Detection Channel: Multi-channel (independent for WBC/DIFF/BASO/NRBC/RET, RBC/PLT).
- Detection Principle: Fluorescence nucleic acid staining + laser scatter + flow cytometry (WBC/DIFF/NRBC/RET), impedance method (RBC/PLT), cyanide-free colorimetric method (HGB).
- Detection Items: 36 parameters including 5-part CBC+DIFF+RET (WBC, NE#, EO#, BA#, MO#, LY#, NE%, EO%, BA%, MO%, LY%, NRBC#, NRBC%, RBC, HGB, HCT, MCV, MCH, MCHC, RDW-SD, RDW-CV, PLT, MPV, PDW, PCT, P-LCR, P-LCC, RET#, RET%, IRF, maturity indices); 4 histograms + scattergram + RET plot; alarms for abnormal/immature cells.
- Built-in thermal printer, supports various types of printer. Multi-builtin print templates available.
- 200,000 sample results, including parameter, histogram, scattergram, RET plot, and patient information.
- Counting modes: Venous whole blood, capillary whole blood, pre-diluted, and body fluid.
