Maccura F880 5-Part Auto Hematology Analyzer
The Maccura F880 is a flagship 5-part hematology analyzer with CBC+DIFF+RET+10-part capabilities, providing up to 100 tests/hour using 88 µL sample volume. Ideal for large-scale labs, it employs 3rd-generation fluorescent dye + flow cytometry for advanced WBC/NRBC diff, laser scatter for RET/IPF, impedance for RBC/PLT, cyanide-free HGB, 10.4-inch touchscreen, 200,000-result storage, and built-in printer. Supports venous, capillary, pre-diluted, body fluid, and low WBC modes with workstation modularity for automated, multi-parameter blood analysis.
Description
5-Part Differentiation: Advanced White Blood Cell Subpopulation Analysis The Maccura F880 applies 3rd-generation fluorescent nucleic acid staining and flow cytometry to perform precise 5-part WBC differentiation, detailing neutrophils (NE# and NE%), eosinophils (EO# and EO%), basophils (BA# and BA%), monocytes (MO# and MO%), and lymphocytes (LY# and LY%). Augmented by dedicated channels for basophils, NRBC, and naive cells, it sensitively identifies immature and atypical populations, facilitating early detection of hematologic malignancies, sepsis-induced shifts, or regenerative responses, with heightened accuracy in high-risk cohorts like transplant recipients or chemotherapy patients.
Parameters Measured: Measures up to 88 parameters (37+ reportable), including expanded CBC, DIFF, RET, and PLT-F panels: WBC, NE#, EO#, BA#, MO#, LY#, NE%, EO%, BA%, MO%, LY%, NRBC#, NRBC%, RBC, HGB (via cyanide-free spectrophotometry for streamlined safety), HCT, MCV, MCH, MCHC, RDW-SD, RDW-CV, PLT, MPV, PDW, PCT, P-LCR, P-LCC, RET#, RET%, IRF, IPF (immature platelet fraction), LW (low WBC mode), and abnormal cell flags. Delivers four histograms (WBC, BASO, RBC, PLT), a 2D scattergram, RET plot, and PLT-F plot for comprehensive visualization, with intelligent alarms for blasts, variants, or maturity indices to accelerate triage of anemias, thrombotic risks, or erythropoietic failures.
Sample Requirements: Requires a minimal 88 µL sample volume, optimizing for high-efficiency testing in adults, pediatrics, or low-volume draws. Accommodates venous whole blood for core routines, capillary blood for on-site urgency (e.g., neonatal heel pricks), pre-diluted for ultra-high linearity, body fluid for effusions, and low WBC mode for immunocompromised samples, preserving cellular morphology across applications with low artifact generation.
Throughput: Processes up to 100 samples per hour for CBC+DIFF+RET, customized for enterprise labs managing 1,500+ tests daily. As part of the modular workstation series, it supports multi-instrument chaining (e.g., with F800/F810) for parallel CBC, RET, and SR testing, featuring 50-tube auto-samplers, barcode-driven tracking, and adaptive reruns to sustain 24/7 operations with <30-second first-result delivery for critical interventions.
Technology: Integrates 3rd-generation fluorescent dye specific to DNA/RNA + hydrodynamic focusing flow cytometry + multi-angle laser scatter for WBC/DIFF/NRBC/RET/PLT-F, electrical impedance for RBC/PLT, and cyanide-free colorimetric method for HGB to advance lab sustainability. Isolated multi-channel processing and molecular staining yield CVs <1% for differentials, while AI-enhanced naive cell screening and IPF calculation align with ICSH/CLSI protocols. The system’s extended modes (e.g., AWS for abnormal WBC) bolster diagnostic depth in oncology or infectious disease panels without ancillary reagents.
User Interface and Storage: Deploys a 10.4-inch high-fidelity color touchscreen with immersive 3D visualizations, workflow automation, and multilingual support (up to 12 languages, including English, Portuguese, Hindi, and Chinese) for intuitive, barrier-free control. Handles 200,000+ results with holistic records—parameters, multi-plots, patient metadata, and QC analytics—in an encrypted, AI-searchable repository. Embedded thermal printer enables dynamic templates for protocol-specific outputs, with USB/LAN/RS232/Ethernet/Modbus for HL7/FHIR LIS integration, tele-review, and exports in PDF/XML/CSV to fulfill CAP/ISO 15189 and GDPR requirements.
Reagent System: Closed system aligned with Maccura’s ultra-stable reagents (e.g., MAK-3rd Gen Fluoro for advanced staining, MAK-IPF for platelets), incorporating 7 on-board slots with RFID tracking, auto-dilution, and waste minimization. Consumption reduced by 65% via precision dispensing, with 6-month stability and dynamic alerts for proactive management; broad linearity (WBC to 500 x 10^9/L) and bi-weekly calibration optimize throughput in workstation ecosystems.
Dimensions and Portability: Modular workstation design at 800 × 900 × 850 mm (W × D × H) weighs 70 kg, scalable for single-unit or multi-module setups with integrated racking. Operates at <65 dB on AC 100–240V with ≤400 VA, resilient to 5–40°C ambient and 20–90% humidity for robust installation in high-throughput cores or networked facilities.
- Throughput: Up to 100 samples/hour (CBC+DIFF+RET+10-part); scalable via workstation.
- Detection Channel: Multi-channel (independent for WBC/DIFF/BASO/NRBC/RET/PLT-F, RBC/PLT).
- Detection Principle: 3rd-gen fluorescent nucleic acid staining + laser scatter + flow cytometry (WBC/DIFF/NRBC/RET/PLT-F), impedance method (RBC/PLT), cyanide-free colorimetric method (HGB).
- Detection Items: Up to 88 parameters including 5-part/10-part CBC+DIFF+RET+PLT-F (WBC, NE#, EO#, BA#, MO#, LY#, NE%, EO%, BA%, MO%, LY%, NRBC#, NRBC%, RBC, HGB, HCT, MCV, MCH, MCHC, RDW-SD, RDW-CV, PLT, MPV, PDW, PCT, P-LCR, P-LCC, RET#, RET%, IRF, IPF, LW, abnormal flags); 4 histograms + scattergram + RET/PLT-F plots; alarms for abnormal/immature/naive cells.
- Built-in thermal printer, supports various types of printer. Multi-builtin print templates available.
- 200,000 sample results, including parameter, histogram, scattergram, RET/PLT-F plots, and patient information.
- Counting modes: Venous whole blood, capillary whole blood, pre-diluted, body fluid, and low WBC.
