Innocheck POCT Immunofluorescence Quantitative Analyzer
The Innocheck POCT is a handheld immunofluorescence analyzer delivering quantitative results in 3–15 minutes for over 50 parameters at up to 60 tests/hour with 20 µL sample volume. Ideal for ERs, clinics, and field use, it features time-resolved fluorescence (TRF) detection, dry reagent strips, 4.3-inch touchscreen, 10,000-result storage, built-in printer, and LIS connectivity for rapid cardiac, infectious, and hormone testing.
Description
Assay Methodologies: Sensitive Immunofluorescence Detection The Innocheck POCT employs time-resolved fluorescence immunoassay (TRF-FIA) with dry reagent strips for competitive and sandwich formats, utilizing europium-labeled antibodies for low-background, high-specificity antigen detection. This enables quick, on-site quantitative analysis of biomarkers in whole blood or fluids, supporting immediate decisions for acute events like MI or infections, with minimal training for non-lab staff in primary care or ambulances.
Parameters Measured: Supports over 50 assays including cardiac markers (cTnI, NT-proBNP, CK-MB, Myo), infectious (CRP, PCT, HBsAg, Anti-HCV, Dengue IgM/IgG), hormones (TSH, FT4, β-hCG, FSH), inflammation (SAA, IL-6), and tumor (CEA, AFP, CA125). Uses 365 nm LED excitation and 615 nm emission for >5-log dynamic range (e.g., 0.01 ng/mL for cTnI), with CV <6% and auto-calibration curves, plus critical alarms for thresholds like CRP >10 mg/L.
Sample Requirements: Requires 20 µL from whole blood (fingerstick/venous), serum, plasma, or urine via strip insertion, eliminating centrifugation or dilution. Barcode on strips ensures lot-specific calibration, with hemolysis detection for quality flags, making it suitable for neonates, geriatrics, or remote testing without sample prep.
Throughput: Processes up to 60 tests per hour in portable mode, optimized for point-of-care sites handling 100–300 tests daily. Each assay runs 3–15 minutes (strip-dependent), with one-step insertion for continuous use during shifts, prioritizing STAT cardiac or infectious results in <5 minutes for triage.
Technology: Leverages TRF with rare-earth chelates for long-decay fluorescence (>500 µs), reducing autofluorescence via PMT gating. Dry strips with immobilized antibodies enable room-temp storage (18 months), while integrated optics and software provide auto-QC and interference correction, aligning with CLSI POCT12-A3 for accuracy comparable to lab CLIA.
User Interface and Storage: Includes a 4.3-inch color touchscreen with icon-driven menus, real-time progress bars, and multilingual support (up to 6 languages, including English and Chinese) for intuitive POC operation. Stores 10,000 results with parameters, trends, and patient IDs in a secure database; built-in mini thermal printer for reports, with USB/Bluetooth for LIS integration and PDF exports to mobile apps.
Reagent System: Dry immunofluorescence strips (25–50 tests/pack) with pre-dried reagents, stable at 2–30°C for 18 months. Auto-recognition via QR codes handles calibration/expiry, with no liquid waste; low-cost per test (<$2) and built-in controls ensure daily verification without refrigeration.
Dimensions and Portability: Handheld design at 180 × 80 × 50 mm (L × W × H) weighs 0.4 kg, fitting in pockets for field or bedside use. Rechargeable battery (8+ hours) with AC adapter, operates quietly (<40 dB) in 0–40°C ambient with 20–90% humidity, ideal for ambulances or rural clinics.
- Throughput: Up to 60 tests/hour
- Detection Channel: Single-channel PMT for TRF.
- Detection Principle: Time-resolved fluorescence immunoassay with dry strips in competitive/sandwich formats.
- Detection Items: Over 50 parameters (cardiac, infectious, hormones, inflammation); alarms for critical levels.
- Built-in mini thermal printer, supports external printers. Multi-builtin report templates available.
- 10,000 sample results, including parameters, calibration curves, QC data, and patient information.
- Sample modes: Whole blood, serum/plasma, urine; strip-based insertion.
