Aikang CCLIA-mate Plus Chemiluminescence Immunoassay Analyzer
The Aikang CCLIA-mate Plus is a compact, fully automated chemiluminescence immunoassay (CLIA) analyzer offering 6-channel parallel detection at up to 60 tests/hour with results in 15 minutes using 50 µL sample volume across over 100 parameters. Designed for POC and small labs, it features magnetic particle CLIA with ALP-AMPPD, all-in-one reagent cartridges, 7-inch touchscreen, 50,000-result storage, and bi-directional LIS integration for fast infectious, cardiac, and hormone screening.
Description
Assay Methodologies: Efficient Immunoassay Processing The Aikang CCLIA-mate Plus employs magnetic particle-based chemiluminescence immunoassay (CLIA) utilizing the ALP-AMPPD reaction system for sandwich and competitive formats, ensuring high-efficiency signal amplification and minimal background noise. This enables rapid qualitative/quantitative detection of biomarkers in serum, plasma, or whole blood, supporting urgent panels like cardiac troponin for AMI or thyroid hormones for endocrine disorders, with streamlined workflows for ERs, clinics, or bedside testing.
Parameters Measured: Supports over 100 assays including infectious diseases (HBsAg, Anti-HCV, HIV Ab, Syphilis TP), cardiac markers (cTnI, NT-proBNP, CK-MB, Myo, D-Dimer), hormones (TSH, FT4, FSH, LH, β-hCG), tumor markers (CEA, AFP, CA125, PSA), inflammation (CRP, PCT), and fertility (AMH). Leverages ALP-AMPPD chemiluminescence for sensitivity down to 0.01 pg/mL (e.g., cTnI), with CV <5% and automated multi-point calibration curves, plus alarms for critical thresholds to flag acute events like sepsis or myocardial injury.
Sample Requirements: Aspirates 50 µL from serum, plasma, whole blood, or fingertip blood via disposable tips, compatible with primary tubes (5 mL) in 50-position racks. Barcode scanning ensures error-free ID, with auto-dilution (up to 1:50) for high samples and no pre-centrifugation needed for whole blood, ideal for rapid POC in pediatrics or remote settings.
Throughput: Achieves up to 60 tests per hour with 6-channel parallel processing, suited for small to mid-sized labs handling 300–600 tests daily. First results available in 15 minutes via continuous random access, with STAT mode for <10-minute cardiac or infectious panels, minimizing delays in high-turnover environments like outpatient departments.
Technology: Integrates magnetic particle separation for precise washing and ALP-AMPPD substrate for stable, high-luminescence signals detected by photomultiplier tubes (PMT), offering >6-log dynamic range. The all-in-one cartridge design combines reagents and consumables to eliminate manual prep, while automated incubation (37°C) and signal processing align with CLSI standards, ensuring low interference and reliable performance in compact POC setups.
User Interface and Storage: Features a 7-inch color touchscreen with intuitive icons, real-time status monitoring, and multilingual support (up to 6 languages, including English and Chinese) for seamless operation. Stores 50,000 results with parameters, curves, patient data, and QC logs in a searchable database; built-in thermal printer for customizable reports, with USB/RS232/LAN ports for HL7 LIS integration and PDF/CSV exports to facilitate digital workflows and compliance.
Reagent System: All-in-one closed cartridges (25–50 tests each) with pre-loaded magnetic particles and ALP-labeled conjugates, refrigerated at 2–8°C for 24-hour stability. Auto-loading and RFID recognition manage inventory/expiry, with low-volume dispensing (<20 µL) reducing waste by 40%; compatible with Aikang’s ready-to-use kits for bi-weekly calibration and two-level QC.
Dimensions and Portability: Portable benchtop unit at 450 × 350 × 500 mm (W × D × H) weighs 25 kg, designed for easy bench or cart placement in space-constrained labs. Low power (≤200 VA) and quiet operation (<50 dB) support 10–30°C ambient with 30–85% humidity, with optional battery for 2-hour mobility in field applications.
- Throughput: Up to 60 tests/hour (6-channel parallel).
- Detection Channel: 6-channel PMT for chemiluminescence.
- Detection Principle: Magnetic particle CLIA with ALP-AMPPD substrate in sandwich/competitive formats.
- Detection Items: Over 100 parameters (infectious, cardiac, hormones, tumor, inflammation); critical alarms and curve fitting.
- Built-in thermal printer, supports external printers. Multi-builtin report templates available.
- 50,000 sample results, including parameters, calibration curves, QC data, and patient information.
- Sample modes: Serum/plasma, whole blood, fingertip blood; auto-dilution and barcode support.
